Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H3A4E9_LATCHUncharacterized protein. (1677 aa)    
Predicted Functional Partners:
ASH2L
ASH2 like, histone lysine methyltransferase complex subunit.
    
 0.979
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit.
    
 0.978
WDR82
WD repeat domain 82.
   
 0.976
CXXC1
CXXC finger protein 1.
   
 0.974
WDR5B
WD repeat domain 5B.
   
 0.944
DPY30
Dpy-30 histone methyltransferase complex regulatory subunit.
    
 0.934
HCFC2
Host cell factor C2.
   
 0.874
HCFC1
Host cell factor C1.
   
 0.874
H4C11
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.862
DIDO1
Death inducer-obliterator 1.
   
 0.858
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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