Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
E2F5E2F transcription factor 5. (378 aa)    
Predicted Functional Partners:
RBL2
RB transcriptional corepressor like 2.
   
 0.992
RBL1
RB transcriptional corepressor like 1.
   
 0.992
TFDP2
Transcription factor.
   
 0.991
TFDP1
Transcription factor.
   
 0.987
RB1
Uncharacterized protein.
   
 0.962
SMAD2
Mothers against decapentaplegic homolog.
    
 0.962
SMAD4
MH2 domain-containing protein.
    
 0.962
SMAD3
Mothers against decapentaplegic homolog.
    
 0.962
LOC102358988
Mothers against decapentaplegic homolog.
    
 0.962
LIN9
Lin-9 DREAM MuvB core complex component.
    
 0.948
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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