Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SNX17Sorting nexin 17. (455 aa)    
Predicted Functional Partners:
VPS26C
VPS26 endosomal protein sorting factor C.
   
 
 0.933
VPS35L
VPS35 endosomal protein sorting factor like.
    
 
 0.930
VPS29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
    
 
 0.904
VPS35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 
 0.853
SNX2
Sorting nexin 2.
   
 
 0.806
STX18
Syntaxin 18.
      
 0.789
TBC1D5
TBC1 domain family member 5.
    
 
 0.760
H3AL78_LATCH
CAP-ZIP_m domain-containing protein.
    
 
 0.729
VPS26A
VPS26, retromer complex component A.
   
 
 0.728
SNX1
PX domain-containing protein.
   
 
 0.702
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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