Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PPM1EProtein phosphatase, Mg2+/Mn2+ dependent 1E. (611 aa)    
Predicted Functional Partners:
LOC102354290
Uncharacterized protein.
  
 
 0.700
FEM1B
Fem-1 homolog B.
   
 
 0.686
FEM1C
Fem-1 homolog C.
   
 
 0.686
FEM1A
Fem-1 homolog A.
   
 
 0.686
WDR90
WD repeat domain 90.
    
   0.651
TMEM134
Transmembrane protein 134.
      
 0.641
RNF170
Ring finger protein 170.
      
 0.641
SLC25A27
Solute carrier family 25 member 27; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.641
PPP1R26
PPP1R26_N domain-containing protein.
      
 0.638
PITPNM1
Phosphatidylinositol transfer protein membrane associated 1.
      
 0.629
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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