Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EVLEnah/Vasp-like. (688 aa)    
Predicted Functional Partners:
ZYX
Zyxin.
   
 0.982
VASP
Vasodilator stimulated phosphoprotein.
    
  0.968
ENAH
ENAH actin regulator.
    
 0.968
PFN4
Profilin; Belongs to the profilin family.
   
 0.830
RAPH1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1.
    
 
 0.794
ARHGEF2
Rho/Rac guanine nucleotide exchange factor 2.
   
   0.758
FBLIM1
Filamin binding LIM protein 1.
    
 0.756
LOC102362556
Profilin; Belongs to the profilin family.
   
 0.723
PFN2
Profilin; Belongs to the profilin family.
   
 0.723
LOC102357963
Profilin; Belongs to the profilin family.
   
 0.723
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.