Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CD68Uncharacterized protein. (373 aa)    
Predicted Functional Partners:
IL6
Uncharacterized protein.
      
 0.941
GFAP
Glial fibrillary acidic protein; Belongs to the intermediate filament family.
   
 
 0.939
IL10
Interleukin 10.
      
 0.921
CSF1R
Colony stimulating factor 1 receptor.
   
  
 0.889
GRN
Granulin precursor.
   
 
 0.820
H3AMW7_LATCH
Uncharacterized protein.
   
 
 0.721
MERTK
MER proto-oncogene, tyrosine kinase.
    
 
 0.719
LOC102348047
Sushi domain-containing protein.
      
 0.715
CTSZ
Cathepsin Z; Belongs to the peptidase C1 family.
   
 
 0.701
AXL
AXL receptor tyrosine kinase.
    
 
 0.701
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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