STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LGI2Leucine rich repeat LGI family member 2. (544 aa)    
Predicted Functional Partners:
ADAM23
ADAM metallopeptidase domain 23.
     
 0.890
ADAM22
ADAM metallopeptidase domain 22.
     
 0.879
H2ZWS3_LATCH
DBF4-type domain-containing protein.
     
 0.667
FBXL17
F-box and leucine rich repeat protein 17.
   
  
 0.618
CECR2
CECR2 histone acetyl-lysine reader.
    
 0.527
CCDC149
Coiled-coil domain containing 149.
 
    
 0.499
AKAP6
Uncharacterized protein.
      
 0.499
KRT18
Keratin 18b; Belongs to the intermediate filament family.
    
 0.463
ADAM8
ADAM metallopeptidase domain 8.
     
 0.444
ADAM28
ADAM metallopeptidase domain 28.
     
 0.444
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.