SLC6A8 protein (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

SLC6A8

Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (641 aa)

Predicted Functional Partners:

LRGUK

0.725

LOC102353081

0.667

ANO6

0.561

SCNN1A

0.541

GAMT

0.531

MEST

0.526

GATM

0.522

SLC25A48

0.486

GNL3L

0.454

MECP2

0.454

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANO6	SCNN1A	ENSLACP00000006114	ENSLACP00000009663	Anoctamin.	Sodium channel epithelial 1 alpha subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.652
ANO6	SLC6A8	ENSLACP00000006114	ENSLACP00000004604	Anoctamin.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.561
GAMT	GATM	ENSLACP00000011879	ENSLACP00000020645	Guanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.	Glycine amidinotransferase.	0.995
GAMT	GNL3L	ENSLACP00000011879	ENSLACP00000011578	Guanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.	G protein nucleolar 3 like.	0.631
GAMT	MECP2	ENSLACP00000011879	ENSLACP00000012808	Guanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.	Methyl-CpG binding protein 2.	0.658
GAMT	SLC6A8	ENSLACP00000011879	ENSLACP00000004604	Guanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.531
GATM	GAMT	ENSLACP00000020645	ENSLACP00000011879	Glycine amidinotransferase.	Guanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.	0.995
GATM	SLC6A8	ENSLACP00000020645	ENSLACP00000004604	Glycine amidinotransferase.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.522
GNL3L	GAMT	ENSLACP00000011578	ENSLACP00000011879	G protein nucleolar 3 like.	Guanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.	0.631
GNL3L	MECP2	ENSLACP00000011578	ENSLACP00000012808	G protein nucleolar 3 like.	Methyl-CpG binding protein 2.	0.896
GNL3L	SLC6A8	ENSLACP00000011578	ENSLACP00000004604	G protein nucleolar 3 like.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.454
LOC102353081	LRGUK	ENSLACP00000000444	ENSLACP00000012879	Uncharacterized protein.	Leucine rich repeats and guanylate kinase domain containing.	0.849
LOC102353081	MEST	ENSLACP00000000444	ENSLACP00000018154	Uncharacterized protein.	Mesoderm specific transcript.	0.808
LOC102353081	SLC6A8	ENSLACP00000000444	ENSLACP00000004604	Uncharacterized protein.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.667
LRGUK	LOC102353081	ENSLACP00000012879	ENSLACP00000000444	Leucine rich repeats and guanylate kinase domain containing.	Uncharacterized protein.	0.849
LRGUK	MEST	ENSLACP00000012879	ENSLACP00000018154	Leucine rich repeats and guanylate kinase domain containing.	Mesoderm specific transcript.	0.786
LRGUK	SLC6A8	ENSLACP00000012879	ENSLACP00000004604	Leucine rich repeats and guanylate kinase domain containing.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.725
MECP2	GAMT	ENSLACP00000012808	ENSLACP00000011879	Methyl-CpG binding protein 2.	Guanidinoacetate N-methyltransferase; Converts guanidinoacetate to creatine, using S- adenosylmethionine as the methyl donor. Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.	0.658
MECP2	GNL3L	ENSLACP00000012808	ENSLACP00000011578	Methyl-CpG binding protein 2.	G protein nucleolar 3 like.	0.896
MECP2	SLC6A8	ENSLACP00000012808	ENSLACP00000004604	Methyl-CpG binding protein 2.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.454