STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (322 aa)    
Predicted Functional Partners:
CCND1
Cyclin D1; Belongs to the cyclin family.
   
 0.996
RB1
Uncharacterized protein.
   
 0.987
CDKN2C
Cyclin dependent kinase inhibitor 2C.
   
 0.986
LOC102345953
Cyclin D3; Belongs to the cyclin family.
   
 0.985
LOC102356560
ANK_REP_REGION domain-containing protein.
    
 0.984
RBL2
RB transcriptional corepressor like 2.
   
 0.971
RBL1
RB transcriptional corepressor like 1.
   
 0.971
CDKN1A
Cyclin dependent kinase inhibitor 1A.
   
 0.968
CDKN1B
Cyclin dependent kinase inhibitor 1B.
   
 0.968
CDKN1C
Uncharacterized protein.
   
 0.968
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.