Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDAREctodysplasin A receptor. (454 aa)    
Predicted Functional Partners:
EDA
Ectodysplasin A; Belongs to the tumor necrosis factor family.
    
 0.999
LEF1
Lymphoid enhancer binding factor 1.
      
 0.779
FGF4
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
      
 0.741
SLC24A5
Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
      
 0.736
BMP4
Bone morphogenetic protein 4.
      
 0.734
FGF20
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
      
 0.701
FGF16
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
      
 0.695
PAX9
Paired box 9.
      
 0.695
TCF7
Transcription factor 7.
      
 0.665
PCNX4
Pecanex 4.
      
 0.626
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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