STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDAREctodysplasin A receptor. (454 aa)    
Predicted Functional Partners:
EDA
Ectodysplasin A; Belongs to the tumor necrosis factor family.
    
 0.999
BMP4
Bone morphogenetic protein 4.
      
 0.672
TCF7
Transcription factor 7.
      
 0.664
LOC102359111
Nanos homolog 1; Belongs to the nanos family.
    
 0.633
NANOS3
Nanos C2HC-type zinc finger 3; Belongs to the nanos family.
    
 0.633
NANOS2
Nanos-type domain-containing protein; Belongs to the nanos family.
    
 0.633
NANOS1
Nanos C2HC-type zinc finger 1; Belongs to the nanos family.
    
 0.633
LEF1
Lymphoid enhancer binding factor 1.
      
 0.588
SLC24A5
Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
      
 0.561
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
      
 0.548
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.