STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDE1BPhosphodiesterase. (469 aa)    
Predicted Functional Partners:
PDE8B
Phosphodiesterase.
     
0.535
ADORA2A
Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.
      
 0.535
PDE8A
Phosphodiesterase.
     
0.535
FAU
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
      
 0.519
LOC102361286
Calmodulin 2; Belongs to the calmodulin family.
    
 0.486
LOC102360791
Uncharacterized protein; Belongs to the calmodulin family.
    
 0.486
CALM2
Calmodulin 2.
    
 0.486
CALM1
Uncharacterized protein; Belongs to the calmodulin family.
    
 0.486
PDE5A
Phosphodiesterase.
    
0.445
PAICS
AIRC domain-containing protein.
      
 0.418
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.