CIITA protein (Latimeria chalumnae) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

CIITA

Class II major histocompatibility complex transactivator. (793 aa)

Predicted Functional Partners:

RFXANK

0.952

PSMC5

0.912

RFXAP

0.840

DEXI

0.715

XPO1

0.710

CD74

0.707

FBXO11

0.653

NWD1

0.626

RRP9

0.613

LHPP

0.609

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD74	CIITA	ENSLACP00000018188	ENSLACP00000004653	CD74 molecule.	Class II major histocompatibility complex transactivator.	0.707
CD74	RFXANK	ENSLACP00000018188	ENSLACP00000016403	CD74 molecule.	Regulatory factor X associated ankyrin containing protein.	0.601
CD74	RFXAP	ENSLACP00000018188	ENSLACP00000013263	CD74 molecule.	Regulatory factor X associated protein.	0.615
CD74	RRP9	ENSLACP00000018188	ENSLACP00000019598	CD74 molecule.	Ribosomal RNA processing 9, U3 small nucleolar RNA binding protein.	0.830
CIITA	CD74	ENSLACP00000004653	ENSLACP00000018188	Class II major histocompatibility complex transactivator.	CD74 molecule.	0.707
CIITA	DEXI	ENSLACP00000004653	ENSLACP00000003607	Class II major histocompatibility complex transactivator.	Dexi homolog.	0.715
CIITA	FBXO11	ENSLACP00000004653	ENSLACP00000016667	Class II major histocompatibility complex transactivator.	F-box protein 11.	0.653
CIITA	LHPP	ENSLACP00000004653	ENSLACP00000016660	Class II major histocompatibility complex transactivator.	Phospholysine phosphohistidine inorganic pyrophosphate phosphatase.	0.609
CIITA	NWD1	ENSLACP00000004653	ENSLACP00000020611	Class II major histocompatibility complex transactivator.	NACHT and WD repeat domain containing 1.	0.626
CIITA	PSMC5	ENSLACP00000004653	ENSLACP00000012044	Class II major histocompatibility complex transactivator.	Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family.	0.912
CIITA	RFXANK	ENSLACP00000004653	ENSLACP00000016403	Class II major histocompatibility complex transactivator.	Regulatory factor X associated ankyrin containing protein.	0.952
CIITA	RFXAP	ENSLACP00000004653	ENSLACP00000013263	Class II major histocompatibility complex transactivator.	Regulatory factor X associated protein.	0.840
CIITA	RRP9	ENSLACP00000004653	ENSLACP00000019598	Class II major histocompatibility complex transactivator.	Ribosomal RNA processing 9, U3 small nucleolar RNA binding protein.	0.613
CIITA	XPO1	ENSLACP00000004653	ENSLACP00000020729	Class II major histocompatibility complex transactivator.	Exportin 1.	0.710
DEXI	CIITA	ENSLACP00000003607	ENSLACP00000004653	Dexi homolog.	Class II major histocompatibility complex transactivator.	0.715
FBXO11	CIITA	ENSLACP00000016667	ENSLACP00000004653	F-box protein 11.	Class II major histocompatibility complex transactivator.	0.653
LHPP	CIITA	ENSLACP00000016660	ENSLACP00000004653	Phospholysine phosphohistidine inorganic pyrophosphate phosphatase.	Class II major histocompatibility complex transactivator.	0.609
LHPP	RRP9	ENSLACP00000016660	ENSLACP00000019598	Phospholysine phosphohistidine inorganic pyrophosphate phosphatase.	Ribosomal RNA processing 9, U3 small nucleolar RNA binding protein.	0.709
NWD1	CIITA	ENSLACP00000020611	ENSLACP00000004653	NACHT and WD repeat domain containing 1.	Class II major histocompatibility complex transactivator.	0.626
PSMC5	CIITA	ENSLACP00000012044	ENSLACP00000004653	Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family.	Class II major histocompatibility complex transactivator.	0.912