Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TLCD3BTLC domain containing 3B. (193 aa)    
Predicted Functional Partners:
CERS2
Ceramide synthase 2.
   
  
 0.739
LRGUK
Leucine rich repeats and guanylate kinase domain containing.
    
 
 0.664
SPHK2
Sphingosine kinase 2.
      
 0.658
MFSD12
Major facilitator superfamily domain containing 12.
   
  
 0.618
PPP1R16B
Protein phosphatase 1 regulatory subunit 16B.
    
 
 0.605
CLN8
CLN8 transmembrane ER and ERGIC protein.
      
 0.588
PPP4C
Serine/threonine-protein phosphatase.
    
 
 0.572
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
   
  
 0.545
SPAG17
Sperm associated antigen 17.
    
 
 0.530
CCDC189
Uncharacterized protein.
    
 
 0.530
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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