Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (573 aa)    
Predicted Functional Partners:
FAU
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
  0.801
KCNAB2
Potassium voltage-gated channel subfamily A regulatory beta subunit 2.
   
 0.716
KCNAB3
Potassium voltage-gated channel subfamily A regulatory beta subunit 3.
   
 0.682
MMACHC
Metabolism of cobalamin associated C.
   
  
 0.659
ATP13A3
Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
   
  
 0.653
EIF2AK4
Eukaryotic translation initiation factor 2 alpha kinase 4.
    
 
 0.578
SCN2B
Sodium voltage-gated channel beta subunit 2.
   
 
 0.566
AKR7L
Aldo-keto reductase family 7 like (gene/pseudogene).
   
 0.559
RPL31
Ribosomal protein L31.
   
 0.553
GABRA2
Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
 
 0.550
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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