Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOXLysyl oxidase. (423 aa)    
Predicted Functional Partners:
LOC102347610
Uncharacterized protein.
 
    
 0.835
IL6
Uncharacterized protein.
    
 0.638
POSTN
Periostin.
   
  
 0.609
FBN1
Fibrillin 1.
   
  
 0.592
MMP9
Matrix metallopeptidase 9.
   
 0.569
TYR
Tyrosinase.
      
 0.544
TGFB1
Transforming growth factor beta; Belongs to the TGF-beta family.
    
 0.543
LPCAT3
Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family.
      
 0.541
CD34
Uncharacterized protein.
      
 0.541
H3ACE0_LATCH
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 0.535
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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