Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EPGNEpithelial mitogen. (161 aa)    
Predicted Functional Partners:
BTC
EGF-like domain-containing protein.
     
 0.799
AREG
Amphiregulin.
     
 0.786
RPS27A
Ribosomal protein S27a.
     
  0.634
FAM83D
Family with sequence similarity 83 member D.
     
  0.634
HBEGF
Heparin binding EGF like growth factor.
     
 0.630
ERBB4
Protein kinase domain-containing protein.
    
 0.627
ERBB3
Protein kinase domain-containing protein.
    
 0.627
ERBB4-2
Protein kinase domain-containing protein.
    
 0.627
H3A7N7_LATCH
GF_recep_IV domain-containing protein.
    
 0.627
ERBB2
Receptor protein-tyrosine kinase.
    
 0.627
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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