Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMEM8BTransmembrane protein 8B. (780 aa)    
Predicted Functional Partners:
IGDCC4
Immunoglobulin superfamily DCC subclass member 4.
      
 0.607
TIMM17B
Translocase of inner mitochondrial membrane 17B.
      
 0.602
TTLL4
Uncharacterized protein.
      
 0.587
TMEM50A
Transmembrane protein 50A.
      
 0.559
ATP1B4
Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.
    
   0.538
ACER1
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
      
 0.448
CFDP1
Craniofacial development protein 1; May play a role during embryogenesis.
      
 0.440
PRKRA
Protein activator of interferon induced protein kinase EIF2AK2.
      
 0.438
TARBP2
TARBP2 subunit of RISC loading complex.
      
 0.438
TIMM17A
Translocase of inner mitochondrial membrane 17A.
      
 0.435
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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