ARFIP1 protein (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ARFIP1

ADP ribosylation factor interacting protein 1. (252 aa)

Predicted Functional Partners:

ARL1

0.875

ARF6

0.711

LOC102349333

0.711

SYNPO2L

0.641

CCDC186

0.641

OCIAD2

0.641

RNF150

0.634

LIAS

0.592

VTI1A

0.556

LOC102351732

0.553

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARF6	ARFIP1	ENSLACP00000005263	ENSLACP00000004736	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	ADP ribosylation factor interacting protein 1.	0.711
ARF6	LOC102349333	ENSLACP00000005263	ENSLACP00000021262	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.900
ARFIP1	ARF6	ENSLACP00000004736	ENSLACP00000005263	ADP ribosylation factor interacting protein 1.	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	0.711
ARFIP1	ARL1	ENSLACP00000004736	ENSLACP00000010525	ADP ribosylation factor interacting protein 1.	ADP ribosylation factor like GTPase 1; Belongs to the small GTPase superfamily. Arf family.	0.875
ARFIP1	CCDC186	ENSLACP00000004736	ENSLACP00000012267	ADP ribosylation factor interacting protein 1.	Coiled-coil domain containing 186.	0.641
ARFIP1	LIAS	ENSLACP00000004736	ENSLACP00000007095	ADP ribosylation factor interacting protein 1.	Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.	0.592
ARFIP1	LOC102349333	ENSLACP00000004736	ENSLACP00000021262	ADP ribosylation factor interacting protein 1.	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.711
ARFIP1	LOC102351732	ENSLACP00000004736	ENSLACP00000006235	ADP ribosylation factor interacting protein 1.	Uncharacterized protein.	0.553
ARFIP1	OCIAD2	ENSLACP00000004736	ENSLACP00000016156	ADP ribosylation factor interacting protein 1.	OCIA domain containing 2.	0.641
ARFIP1	RNF150	ENSLACP00000004736	ENSLACP00000006977	ADP ribosylation factor interacting protein 1.	Ring finger protein 150.	0.634
ARFIP1	SYNPO2L	ENSLACP00000004736	ENSLACP00000005929	ADP ribosylation factor interacting protein 1.	Synaptopodin 2 like.	0.641
ARFIP1	VTI1A	ENSLACP00000004736	ENSLACP00000013287	ADP ribosylation factor interacting protein 1.	Vesicle transport through interaction with t-SNAREs 1A.	0.556
ARL1	ARFIP1	ENSLACP00000010525	ENSLACP00000004736	ADP ribosylation factor like GTPase 1; Belongs to the small GTPase superfamily. Arf family.	ADP ribosylation factor interacting protein 1.	0.875
ARL1	VTI1A	ENSLACP00000010525	ENSLACP00000013287	ADP ribosylation factor like GTPase 1; Belongs to the small GTPase superfamily. Arf family.	Vesicle transport through interaction with t-SNAREs 1A.	0.686
CCDC186	ARFIP1	ENSLACP00000012267	ENSLACP00000004736	Coiled-coil domain containing 186.	ADP ribosylation factor interacting protein 1.	0.641
CCDC186	VTI1A	ENSLACP00000012267	ENSLACP00000013287	Coiled-coil domain containing 186.	Vesicle transport through interaction with t-SNAREs 1A.	0.872
LIAS	ARFIP1	ENSLACP00000007095	ENSLACP00000004736	Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.	ADP ribosylation factor interacting protein 1.	0.592
LIAS	OCIAD2	ENSLACP00000007095	ENSLACP00000016156	Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.	OCIA domain containing 2.	0.683
LIAS	RNF150	ENSLACP00000007095	ENSLACP00000006977	Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.	Ring finger protein 150.	0.579
LIAS	SYNPO2L	ENSLACP00000007095	ENSLACP00000005929	Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.	Synaptopodin 2 like.	0.696