Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
APLP1Amyloid beta (A4) precursor-like protein 1. (699 aa)    
Predicted Functional Partners:
APP
Amyloid beta precursor protein.
    
 
 0.922
SORL1
Sortilin-related receptor, L(DLR class) A repeats containing.
    
 0.864
SDHAF1
Uncharacterized protein; Belongs to the complex I LYR family.
      
 0.810
APBB1
Uncharacterized protein.
    
 0.805
H3ABB9_LATCH
WW domain-containing protein.
    
 0.805
H3AEU7_LATCH
Uncharacterized protein.
    
 0.805
APBB2
Amyloid beta precursor protein binding family B member 2.
    
 0.805
FKRP
Fukutin related protein.
     
 0.799
CCNE1
Cyclin E1; Belongs to the cyclin family.
      
 0.791
LOC102353503
Uncharacterized protein.
    
 0.752
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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