Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (435 aa)    
Predicted Functional Partners:
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
   
 0.939
H3B6K7_LATCH
IKKbetaNEMObind domain-containing protein.
   
 0.923
LTA
Lymphotoxin alpha.
    
 0.736
TAB2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
    
 0.727
N4BP1
NEDD4 binding protein 1.
    
  0.710
H3AC12_LATCH
RNase_Zc3h12a domain-containing protein.
    
  0.707
TBK1
TANK binding kinase 1.
   
 0.690
CYLD
CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family.
    
 0.667
TAB3
TGF-beta activated kinase 1 (MAP3K7) binding protein 3.
    
 0.663
FAM189A2
Family with sequence similarity 189 member A2.
   
 0.648
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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