Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H3A551_LATCHPhosphodiesterase. (437 aa)    
Predicted Functional Partners:
TRIM32
Tripartite motif containing 32.
    
   0.766
PDE6G
Phosphodiesterase 6G.
   
 0.667
LOC102362951
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.
   
 0.570
PRKX
Protein kinase X-linked; Belongs to the protein kinase superfamily.
   
 0.570
PRKACB
Uncharacterized protein; Belongs to the protein kinase superfamily.
   
 0.570
PHLPP2
PH domain and leucine rich repeat protein phosphatase 2.
   
 
 0.547
H3AYB6_LATCH
Uncharacterized protein.
   
 0.516
NF1
Neurofibromin 1.
   
 
 0.459
TFAP4
Transcription factor AP-4.
    
   0.425
PPP1R1B
Protein phosphatase 1 regulatory inhibitor subunit 1B.
     
 0.419
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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