STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHANK3SH3 and multiple ankyrin repeat domains 3. (1187 aa)    
Predicted Functional Partners:
DLGAP3
DLG associated protein 3.
   
 0.971
DLGAP2
DLG associated protein 2.
   
 0.964
LOC102363797
Uncharacterized protein.
 
  
 0.952
DLGAP1
DLG associated protein 1.
   
 0.921
HOMER1
Homer scaffold protein 1.
    
 0.862
DLGAP4
DLG associated protein 4.
    
 0.839
NRXN2
Uncharacterized protein.
   
 
 0.831
RAP1B
RAP1B, member of RAS oncogene family.
    
 0.786
RAP1A
RAP1A, member of RAS oncogene family b.
    
 0.786
H2ZSE1_LATCH
Uncharacterized protein.
    
 0.760
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.