DDIT4L protein (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

DDIT4L

DNA damage inducible transcript 4 like. (187 aa)

Predicted Functional Partners:

TSC2

0.880

RRAGB

0.451

RPTOR

0.448

H2ZV93_LATCH

0.428

YWHAZ

0.428

YWHAG

0.428

YWHAB

0.428

YWHAQ

0.428

YWHAH

0.428

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDIT4L	H2ZV93_LATCH	ENSLACP00000004852	ENSLACP00000001314	DNA damage inducible transcript 4 like.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.428
DDIT4L	RPTOR	ENSLACP00000004852	ENSLACP00000023161	DNA damage inducible transcript 4 like.	Regulatory associated protein of MTOR complex 1.	0.448
DDIT4L	RRAGB	ENSLACP00000004852	ENSLACP00000018240	DNA damage inducible transcript 4 like.	Ras-related GTP binding A.	0.451
DDIT4L	TSC2	ENSLACP00000004852	ENSLACP00000000293	DNA damage inducible transcript 4 like.	TSC complex subunit 2.	0.880
DDIT4L	YWHAB	ENSLACP00000004852	ENSLACP00000007313	DNA damage inducible transcript 4 like.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family.	0.428
DDIT4L	YWHAG	ENSLACP00000004852	ENSLACP00000006182	DNA damage inducible transcript 4 like.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family.	0.428
DDIT4L	YWHAH	ENSLACP00000004852	ENSLACP00000019805	DNA damage inducible transcript 4 like.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family.	0.428
DDIT4L	YWHAQ	ENSLACP00000004852	ENSLACP00000011891	DNA damage inducible transcript 4 like.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.428
DDIT4L	YWHAZ	ENSLACP00000004852	ENSLACP00000001531	DNA damage inducible transcript 4 like.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.428
H2ZV93_LATCH	DDIT4L	ENSLACP00000001314	ENSLACP00000004852	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	DNA damage inducible transcript 4 like.	0.428
H2ZV93_LATCH	RPTOR	ENSLACP00000001314	ENSLACP00000023161	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	Regulatory associated protein of MTOR complex 1.	0.549
H2ZV93_LATCH	RRAGB	ENSLACP00000001314	ENSLACP00000018240	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	Ras-related GTP binding A.	0.481
H2ZV93_LATCH	TSC2	ENSLACP00000001314	ENSLACP00000000293	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	TSC complex subunit 2.	0.798
H2ZV93_LATCH	YWHAG	ENSLACP00000001314	ENSLACP00000006182	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family.	0.687
H2ZV93_LATCH	YWHAH	ENSLACP00000001314	ENSLACP00000019805	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family.	0.687
RPTOR	DDIT4L	ENSLACP00000023161	ENSLACP00000004852	Regulatory associated protein of MTOR complex 1.	DNA damage inducible transcript 4 like.	0.448
RPTOR	H2ZV93_LATCH	ENSLACP00000023161	ENSLACP00000001314	Regulatory associated protein of MTOR complex 1.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.549
RPTOR	RRAGB	ENSLACP00000023161	ENSLACP00000018240	Regulatory associated protein of MTOR complex 1.	Ras-related GTP binding A.	0.998
RPTOR	TSC2	ENSLACP00000023161	ENSLACP00000000293	Regulatory associated protein of MTOR complex 1.	TSC complex subunit 2.	0.926
RPTOR	YWHAB	ENSLACP00000023161	ENSLACP00000007313	Regulatory associated protein of MTOR complex 1.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family.	0.676