Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
APBB1Uncharacterized protein. (241 aa)    
Predicted Functional Partners:
APP
Amyloid beta precursor protein.
    
 0.841
KAT5
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
   
 0.813
APLP2
Amyloid beta precursor like protein 2.
    
 0.808
APLP1
Amyloid beta (A4) precursor-like protein 1.
    
 0.805
QTRT1
Queuine tRNA-ribosyltransferase catalytic subunit 1.
    
   0.665
H2ZSE1_LATCH
Uncharacterized protein.
   
 0.571
TRIT1
tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family.
 
 
    0.569
COPS3
COP9 signalosome subunit 3.
    
 0.559
FAM83D
Family with sequence similarity 83 member D.
   
 
 0.552
MAPK10
Mitogen-activated protein kinase 10.
    
 0.534
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.