Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HAND2Heart and neural crest derivatives expressed 2. (210 aa)    
Predicted Functional Partners:
SMYD1
SET and MYND domain containing 1.
    
 0.808
VCL
Vinculin.
      
 0.793
TBX20
T-box transcription factor 20.
   
 
 0.788
EDN1
Endothelin 1.
      
 0.786
TBX5
T-box transcription factor 5.
    
 0.784
NKX2-5
NK2 homeobox 5.
   
 0.778
GLI3
GLI family zinc finger 3.
    
 
 0.763
FGF8
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
 0.729
MYL7
Myosin light chain 7.
      
 0.715
TBX4
T-box transcription factor 4.
    
 0.705
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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