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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
H3A5F1_LATCHUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)    
Predicted Functional Partners:
TRIP12
Thyroid hormone receptor interactor 12.
   
 0.954
UBE2V2-2
Ubiquitin-conjugating enzyme E2 variant 2.
   
 0.902
UBE2V1
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 0.902
RNF8
E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]
   
 0.819
ANAPC11
APC11 anaphase promoting complex subunit 11 homolog (yeast).
    
 0.797
OTUB1
Ubiquitin thioesterase.
   
 0.795
UBE2V2
Ubiquitin conjugating enzyme E2 V2.
   
 0.783
RPS27A
Ribosomal protein S27a.
   
 0.772
UBA1
Ubiquitin-like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family.
  
 0.768
UBA7
Uncharacterized protein; Belongs to the ubiquitin-activating E1 family.
  
 0.768
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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