Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EPM2AEPM2A glucan phosphatase, laforin. (228 aa)    
Predicted Functional Partners:
NHLRC1
NHL repeat containing E3 ubiquitin protein ligase 1.
    
 0.969
M3XJQ7_LATCH
CBM20 domain-containing protein.
    
 
 0.932
H2ZSK8_LATCH
TYR_PHOSPHATASE_2 domain-containing protein.
 
     0.921
PRKAB2
Protein kinase AMP-activated non-catalytic subunit beta 2.
   
 
 0.778
GYS2
Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.
    
 0.594
AGL
Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase.
    
 
 0.560
NFU1
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae).
   
 
 0.557
PRKAB1
Protein kinase AMP-activated non-catalytic subunit beta 1.
   
 
 0.547
TAT
Tyrosine aminotransferase.
   
  
 0.533
SLC5A10
Solute carrier family 5 member 10; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
      
 0.526
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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