Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
H3A5I8_LATCHABC transporter domain-containing protein. (665 aa)    
Predicted Functional Partners:
LOC102361283
ATP-binding cassette, sub-family G (WHITE), member 2b.
  
  
 
0.904
ABCG2
ABC transporter domain-containing protein.
  
  
 
0.901
H3AIJ4_LATCH
Uncharacterized protein.
   
 0.881
ABCG5
ATP binding cassette subfamily G member 5.
   
 0.735
ABCC1
ATP binding cassette subfamily C member 1.
   
 0.614
H3AES0_LATCH
ATP-binding cassette, sub-family C (CFTR/MRP), member 3.
   
 0.614
LOC102348428
Uncharacterized protein.
   
 0.614
ABCC3
ATP-binding cassette, sub-family C (CFTR/MRP), member 3.
   
 0.558
CFTR
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
   
 0.534
ZFAT
Zinc finger and AT-hook domain containing.
   
 
 0.507
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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