STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOCK8Dedicator of cytokinesis 8; Belongs to the DOCK family. (2039 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
   
 0.976
RHOQ
Ras homolog family member Q.
   
 0.638
RHOJ
Ras homolog family member J.
   
 0.638
LOC102351732
Uncharacterized protein.
   
 0.618
RAC1
Rac family small GTPase 1.
   
 0.618
RAC3
Rac family small GTPase 3.
   
 0.618
MET
MET proto-oncogene, receptor tyrosine kinase.
   
 
  0.596
H2ZSF9_LATCH
Uncharacterized protein.
   
  
 0.584
HNRNPR
Heterogeneous nuclear ribonucleoprotein R.
      
 0.536
SYNCRIP
Synaptotagmin binding cytoplasmic RNA interacting protein.
      
 0.536
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.