Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PKD2Polycystin 2, transient receptor potential cation channel. (890 aa)    
Predicted Functional Partners:
PKD1
Polycystin 1, transient receptor potential channel interacting.
   
0.989
H3B277_LATCH
Uncharacterized protein.
   
 0.985
TRPC1
Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family.
    
 
 0.868
IBSP
Uncharacterized protein.
   
 
 0.823
IFT20
Intraflagellar transport 20.
   
  
 0.815
PKHD1
PKHD1 ciliary IPT domain containing fibrocystin/polyductin.
      
 0.775
H3A0G5_LATCH
Uncharacterized protein.
    
 
 0.773
EXOC5
Exocyst complex component 5.
     
 0.756
NUDT9
Nudix hydrolase 9.
      
 0.735
IFT140
Intraflagellar transport 140.
      
 0.708
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.