Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
OSBPL3Oxysterol-binding protein; Belongs to the OSBP family. (855 aa)    
Predicted Functional Partners:
VAPB
VAMP associated protein B and C.
    
 
 0.661
GAK
J domain-containing protein.
   
 
 0.653
VAPA
VAMP associated protein A.
    
 
 0.561
MOSPD1
Motile sperm domain containing 1.
    
 
 0.521
APAF1
Apoptotic peptidase activating factor 1.
      
 0.513
CASP9
Caspase 9; Belongs to the peptidase C14A family.
      
 0.513
DNAJC6
DnaJ heat shock protein family (Hsp40) member C6.
    
 
 0.478
NDUFA12
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
   
  
 0.472
ABCF1
ATP binding cassette subfamily F member 1.
   
  
 0.470
AGBL5
ATP/GTP binding protein like 5.
      
 0.468
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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