Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC102349972Uncharacterized protein. (246 aa)    
Predicted Functional Partners:
GRIN2B
Glutamate ionotropic receptor NMDA type subunit 2B.
   
 0.900
DLG2
Guanylate kinase-like domain-containing protein.
 
      0.899
DLGAP1
DLG associated protein 1.
   
 0.894
GRIN2A
Glutamate ionotropic receptor NMDA type subunit 2A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
   
 0.869
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
   
 0.843
DLGAP2
DLG associated protein 2.
   
 0.827
GRIA1
Glutamate ionotropic receptor AMPA type subunit 1.
   
 0.826
LRFN2
Leucine rich repeat and fibronectin type III domain containing 2.
   
 0.812
DLGAP3
DLG associated protein 3.
   
 0.795
MDM2
E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.
    
 0.773
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (8%) [HD]