Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC102345552Carbonic anhydrase 15; Belongs to the alpha-carbonic anhydrase family. (307 aa)    
Predicted Functional Partners:
DGCR2
DiGeorge syndrome critical region gene 2.
 
    
 0.704
NXPH1
Neurexophilin; May be signaling molecules that resemble neuropeptides.
   
  
 0.659
NXPH2
Neurexophilin; May be signaling molecules that resemble neuropeptides.
   
  
 0.659
RPF2
Ribosome production factor 2 homolog.
   
 
 0.582
LEP
Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family.
      
 0.572
GRWD1
Glutamate rich WD repeat containing 1.
   
  
 0.505
CA14
Carbonic anhydrase 14; Belongs to the alpha-carbonic anhydrase family.
     
  0.493
CA12
Carbonic anhydrase 12; Belongs to the alpha-carbonic anhydrase family.
     
  0.493
NOC2L
Uncharacterized protein.
   
  
 0.462
WDR43
WD repeat domain 43.
   
    0.460
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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