STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (478 aa)    
Predicted Functional Partners:
PDPK1
3-phosphoinositide dependent protein kinase 1.
   
0.989
MDM2
E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family.
    
 0.980
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
   
0.978
TSC2
TSC complex subunit 2.
    
 0.977
AKT1S1
AKT1 substrate 1.
   
 0.977
CDKN1A
Cyclin dependent kinase inhibitor 1A.
    
 0.971
FOXO4
Forkhead box O4.
    
 0.971
FOXO1
Forkhead box O1.
    
 0.971
FOXO6-2
Fork-head domain-containing protein.
    
 0.971
FOXO3
Fork-head domain-containing protein.
    
 0.971
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.