Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
NAMPTNicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (492 aa)    
Predicted Functional Partners:
NMNAT1
Nicotinamide-nucleotide adenylyltransferase.
     
 0.985
SIRT1
Sirtuin 1.
     
 0.981
NMNAT2
Nicotinamide nucleotide adenylyltransferase 2.
     
 0.965
SIRT3
NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.
     
 0.961
NMRK1
Nicotinamide riboside kinase 1.
  
 
 0.958
SIRT6
Sirtuin 6.
     
 0.952
SIRT4
NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.
     
 0.951
SARM1
Sterile alpha and TIR motif containing 1.
     
 0.944
SIRT5
NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.
     
 0.940
H3BDU0_LATCH
NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.
     
 0.935
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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