STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NAMPTNicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (492 aa)    
Predicted Functional Partners:
NMNAT1
Nicotinamide-nucleotide adenylyltransferase.
     
 0.979
SIRT6
Sirtuin 6.
     
 0.954
NMNAT2
Nicotinamide nucleotide adenylyltransferase 2.
     
 0.951
SIRT4
NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.
     
 0.949
SIRT3
NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.
     
 0.948
NMRK1
Nicotinamide riboside kinase 1.
  
 
 0.942
SIRT5
NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.
     
 0.939
SIRT7
Sirtuin 7.
     
 0.932
H3BDU0_LATCH
NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.
     
 0.925
LOC102356827
Uncharacterized protein.
  
 
 0.922
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.