Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NKX1-1NK1 homeobox 1. (398 aa)    
Predicted Functional Partners:
CREB3L1
cAMP responsive element binding protein 3 like 1.
      
 0.926
DIRAS1
DIRAS family GTPase 1.
     
 0.642
DIRAS2
DIRAS family GTPase 2.
     
 0.642
TMEM120B
Transmembrane protein 120B.
      
 0.636
TMEM120A
Transmembrane protein 120A.
      
 0.636
LCAT
Lecithin-cholesterol acyltransferase.
      
 0.627
CCDC155
Uncharacterized protein.
    
 
 0.614
DMC1
Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily.
      
 0.594
HEY2
Hes related family bHLH transcription factor with YRPW motif 2.
      
 0.590
HEYL
Hes related family bHLH transcription factor with YRPW motif like.
      
 0.590
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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