Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PHLPP2PH domain and leucine rich repeat protein phosphatase 2. (1186 aa)    
Predicted Functional Partners:
SUGT1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.
    
 
 0.959
WDR48
WD repeat domain 48.
   
 
 0.957
SNX27
Sorting nexin 27.
    
 
 0.937
USP1
Ubiquitin specific peptidase 1; Belongs to the peptidase C19 family.
    
 
 0.927
WDR20
WD repeat domain 20.
    
 
 0.830
DMWD
DM1 locus, WD repeat containing.
    
 
 0.830
CAP2
Adenylyl cyclase-associated protein; Belongs to the CAP family.
    
 
 0.827
CAP1
Adenylyl cyclase-associated protein; Belongs to the CAP family.
    
 
 0.827
USP46
Ubiquitin specific peptidase 46; Belongs to the peptidase C19 family.
    
 
 0.802
LOC102363119
USP domain-containing protein; Belongs to the peptidase C19 family.
    
 
 0.802
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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