STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CORO1ACoronin; Belongs to the WD repeat coronin family. (482 aa)    
Predicted Functional Partners:
H3A1J1_LATCH
WD_REPEATS_REGION domain-containing protein.
 
    
0.797
VASP
Vasodilator stimulated phosphoprotein.
   
  
 0.582
LOC102360750
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
 
 0.568
LOC102363109
Destrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family.
   
 
 0.568
LOC102360491
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
 
 0.568
CFL2
Cofilin 2; Belongs to the actin-binding proteins ADF family.
   
 
 0.564
FPGS
Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.
    
 0.532
RFK
Riboflavin kinase.
  
 
 0.513
CALM2
Calmodulin 2.
    
 
 0.502
ALDH18A1
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
     
 0.498
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.