STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDK2AP2Cyclin dependent kinase 2 associated protein 2. (101 aa)    
Predicted Functional Partners:
GATAD2A
GATA zinc finger domain containing 2A.
    
 
 0.739
GATAD2B
GATA zinc finger domain containing 2B.
    
 
 0.727
MBD2
Methyl-CpG binding domain protein 2.
   
 
 0.708
MBD3
Methyl-CpG binding domain protein 3a.
   
 
 0.708
MTA3
Metastasis associated 1 family member 3.
    
 
 0.595
MTA2
Metastasis associated 1 family member 2.
    
 
 0.595
MTA1
Metastasis associated 1.
    
 
 0.595
HDAC3
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
   
 
 0.586
HDAC8
Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 
 0.586
HDAC1
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 
 0.586
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.