Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H3A6A5_LATCHSerine/threonine-protein phosphatase. (522 aa)    
Predicted Functional Partners:
CHP2
Calcineurin like EF-hand protein 2.
   
 0.739
SNN
Stannin.
      
 0.738
LOC102354410
RHD domain-containing protein.
    
 0.732
NFATC1
Nuclear factor of activated T cells 1.
    
 0.732
NFATC2
Nuclear factor of activated T cells 2.
    
 0.696
RCAN1
Regulator of calcineurin 1.
    
 
 0.685
LOC102360791
Uncharacterized protein; Belongs to the calmodulin family.
    
 0.682
LOC102361286
Calmodulin 2; Belongs to the calmodulin family.
    
 0.680
NFATC3
Nuclear factor of activated T cells 3.
    
 0.654
CHP1
Calcineurin like EF-hand protein 1.
   
 0.653
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (20%) [HD]