Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MAD2L1BPMAD2L1 binding protein. (419 aa)    
Predicted Functional Partners:
TRIP13
Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family.
    
 
 0.981
MAD2L1
Mitotic arrest deficient 2 like 1.
   
 
 0.970
MAD1L1
Mitotic arrest deficient 1 like 1.
    
 
 0.941
INPP5K
Inositol polyphosphate-5-phosphatase K.
    
 
 0.938
LBR
Lamin B receptor.
    
   0.903
H3B376_LATCH
Uncharacterized protein.
    
   0.809
CDC20
Cell division cycle 20.
    
 
 0.799
CDC20B
Cell division cycle 20B.
    
 
 0.799
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
    
 
 0.730
NUBP2
Cytosolic Fe-S cluster assembly factor NUBP2; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
    
   0.695
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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