STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPHKAPSPHK1 interactor, AKAP domain containing. (1592 aa)    
Predicted Functional Partners:
VRK1
VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily.
   
  
 0.556
PTPN2
Tyrosine-protein phosphatase non-receptor type.
      
 0.444
H2ZST5_LATCH
Phospholipase B-like; Putative phospholipase.
      
 0.428
PLBD2
Phospholipase B-like; Putative phospholipase.
      
 0.428
GPNMB
Glycoprotein nmb.
  
   
 0.425
AKAP10
A-kinase anchoring protein 10.
      
 0.420
DEPDC5
DEP domain containing 5.
      
 0.418
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.