Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPHKAPSPHK1 interactor, AKAP domain containing. (1592 aa)    
Predicted Functional Partners:
TSNAXIP1
Translin-associated factor X interacting protein 1.
      
 0.629
SPRED3
Sprouty related EVH1 domain containing 3.
      
 0.614
CCNL1
Cyclin L1; Belongs to the cyclin family.
      
 0.594
PARD6A
Par-6 family cell polarity regulator alpha.
      
 0.588
VRK1
VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily.
      
 0.585
SLC16A7
Solute carrier family 16 member 7.
      
 0.578
MEIOC
Meiosis specific with coiled-coil domain.
      
 0.562
AKAP10
A-kinase anchoring protein 10.
      
 0.559
BCAR1
BCAR1 scaffold protein, Cas family member.
      
 0.549
DEPDC5
DEP domain containing 5.
      
 0.515
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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