STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCNK12Ion_trans_2 domain-containing protein. (301 aa)    
Predicted Functional Partners:
H3AD36_LATCH
Uncharacterized protein.
 
      0.899
FBXO11
F-box protein 11.
      
 0.762
ERLEC1
Endoplasmic reticulum lectin 1.
      
 0.740
PSME4
Proteasome activator subunit 4.
      
 0.724
LOC102360187
MutS homolog 2 (E. coli).
      
 0.623
H2ZX83_LATCH
MutS homolog 2 (E. coli).
      
 0.623
PRPH2
Peripherin 2.
      
 0.606
THBS2
Uncharacterized protein.
      
 0.591
MERTK
MER proto-oncogene, tyrosine kinase.
      
 0.578
KCNK4
Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
0.578
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.