Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHG7Chromosome 12 open reading frame 74. (450 aa)    
Predicted Functional Partners:
WDFY3
Uncharacterized protein.
    
 0.756
LTA
Lymphotoxin alpha.
    
 0.659
TRADD
Death domain-containing protein.
    
 0.611
LYST
Lysosomal trafficking regulator.
    
 0.585
ARHGEF33
DH domain-containing protein.
    
 0.482
ARHGEF38
Rho guanine nucleotide exchange factor 38.
     
 0.468
EFCAB1
EF-hand calcium binding domain 1.
      
 0.467
H2ZS97_LATCH
TNF_2 domain-containing protein.
    
 0.436
TNFSF15
TNF superfamily member 15.
    
 0.436
LOC102361141
TNF_2 domain-containing protein.
    
 0.436
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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