Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
H3A6L2_LATCHNAD(P)(+)--arginine ADP-ribosyltransferase. (253 aa)    
Predicted Functional Partners:
PARP11
Poly [ADP-ribose] polymerase.
      
 0.726
PARP10
Poly [ADP-ribose] polymerase.
      
 0.665
PARP14
Poly [ADP-ribose] polymerase.
      
 0.659
PARP12
Poly(ADP-ribose) polymerase family member 12.
      
 0.659
NAB2
NGFI-A binding protein 2.
      
 0.525
APLF
FHA_2 domain-containing protein.
      
 0.477
CHFR
Checkpoint with forkhead and ring finger domains.
      
 0.435
PARP4
Poly [ADP-ribose] polymerase.
      
 0.427
ADPRHL2
ADP-ribose glycohydrolase ARH3; ADP-ribose glycohydrolase that preferentially hydrolyzes the scissile alpha-O-linkage attached to the anomeric C1'' position of ADP- ribose and acts on different substrates, such as proteins ADP- ribosylated on serine, free poly(ADP-ribose) and O-acetyl-ADP-D-ribose. Specifically acts as a serine mono-ADP- ribosylhydrolase by mediating the removal of mono-ADP-ribose attached to serine residues on proteins, thereby playing a key role in DNA damage response. Serine ADP-ribosylation of proteins constitutes the primary form of ADP-ribosylation of proteins in [...]
      
 0.427
PARP3
Poly [ADP-ribose] polymerase.
      
 0.426
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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