Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KIDINS220Kinase D interacting substrate 220. (1774 aa)    
Predicted Functional Partners:
CRK
CRK proto-oncogene, adaptor protein.
    
 0.800
H3BD64_LATCH
Xenotropic and polytropic retrovirus receptor 1b.
   
 
 0.800
MBOAT2
Membrane bound O-acyltransferase domain containing 2; Belongs to the membrane-bound acyltransferase family.
    
 
 0.717
H3B9T5_LATCH
Uncharacterized protein.
   
 
 0.715
LOC102364341
Uncharacterized protein.
    
 0.658
CRKL
CRK like proto-oncogene, adaptor protein.
    
 0.658
SNX27
Sorting nexin 27.
    
 
 0.605
RND2
Rho family GTPase 2.
    
  0.574
RSPH1
Radial spoke head component 1.
    
 0.557
ID2
Inhibitor of DNA binding 2.
      
 0.534
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.