Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
ABCD3ATP binding cassette subfamily D member 3. (684 aa)    
Predicted Functional Partners:
PEX19
Peroxisomal biogenesis factor 19.
    
 0.996
PEX3
Peroxisomal biogenesis factor 3.
   
 0.945
RAD51
DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]
   
   0.927
ABCD1
ATP binding cassette subfamily D member 1.
  
0.926
ABCD2
ATP binding cassette subfamily D member 2.
   
 0.914
PEX13
SH3 domain-containing protein.
   
 
 0.905
PEX16
Peroxisomal membrane protein PEX16.
     
 0.883
PEX2
Peroxisomal biogenesis factor 2.
    
 0.854
PEX14
Peroxisomal biogenesis factor 14.
   
 0.844
PEX12
Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family.
   
 
 0.844
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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