LRIT3 protein (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LRIT3

Leucine rich repeat, Ig-like and transmembrane domains 3. (651 aa)

Predicted Functional Partners:

RRH

0.824

PTK7

0.766

NTNG1

0.738

ADGRL2

0.730

ADGRL1-2

0.730

ADGRL1

0.730

ADGRL3

0.730

MET

0.707

RIPK4

0.686

RNASEL

0.682

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADGRL1	ADGRL1-2	ENSLACP00000015375	ENSLACP00000014294	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Uncharacterized protein.	0.921
ADGRL1	LRIT3	ENSLACP00000015375	ENSLACP00000005303	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Leucine rich repeat, Ig-like and transmembrane domains 3.	0.730
ADGRL1-2	ADGRL1	ENSLACP00000014294	ENSLACP00000015375	Uncharacterized protein.	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	0.921
ADGRL1-2	LRIT3	ENSLACP00000014294	ENSLACP00000005303	Uncharacterized protein.	Leucine rich repeat, Ig-like and transmembrane domains 3.	0.730
ADGRL2	LRIT3	ENSLACP00000004019	ENSLACP00000005303	Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family.	Leucine rich repeat, Ig-like and transmembrane domains 3.	0.730
ADGRL3	LRIT3	ENSLACP00000023195	ENSLACP00000005303	Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.	Leucine rich repeat, Ig-like and transmembrane domains 3.	0.730
LRIT3	ADGRL1	ENSLACP00000005303	ENSLACP00000015375	Leucine rich repeat, Ig-like and transmembrane domains 3.	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	0.730
LRIT3	ADGRL1-2	ENSLACP00000005303	ENSLACP00000014294	Leucine rich repeat, Ig-like and transmembrane domains 3.	Uncharacterized protein.	0.730
LRIT3	ADGRL2	ENSLACP00000005303	ENSLACP00000004019	Leucine rich repeat, Ig-like and transmembrane domains 3.	Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family.	0.730
LRIT3	ADGRL3	ENSLACP00000005303	ENSLACP00000023195	Leucine rich repeat, Ig-like and transmembrane domains 3.	Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.	0.730
LRIT3	MET	ENSLACP00000005303	ENSLACP00000015263	Leucine rich repeat, Ig-like and transmembrane domains 3.	MET proto-oncogene, receptor tyrosine kinase.	0.707
LRIT3	NTNG1	ENSLACP00000005303	ENSLACP00000011749	Leucine rich repeat, Ig-like and transmembrane domains 3.	Netrin G1.	0.738
LRIT3	PTK7	ENSLACP00000005303	ENSLACP00000015519	Leucine rich repeat, Ig-like and transmembrane domains 3.	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.766
LRIT3	RIPK4	ENSLACP00000005303	ENSLACP00000018007	Leucine rich repeat, Ig-like and transmembrane domains 3.	Receptor interacting serine/threonine kinase 4.	0.686
LRIT3	RNASEL	ENSLACP00000005303	ENSLACP00000000894	Leucine rich repeat, Ig-like and transmembrane domains 3.	Uncharacterized protein.	0.682
LRIT3	RRH	ENSLACP00000005303	ENSLACP00000002426	Leucine rich repeat, Ig-like and transmembrane domains 3.	Retinal pigment epithelium-derived rhodopsin homolog; Belongs to the G-protein coupled receptor 1 family.	0.824
MET	LRIT3	ENSLACP00000015263	ENSLACP00000005303	MET proto-oncogene, receptor tyrosine kinase.	Leucine rich repeat, Ig-like and transmembrane domains 3.	0.707
MET	PTK7	ENSLACP00000015263	ENSLACP00000015519	MET proto-oncogene, receptor tyrosine kinase.	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.664
MET	RIPK4	ENSLACP00000015263	ENSLACP00000018007	MET proto-oncogene, receptor tyrosine kinase.	Receptor interacting serine/threonine kinase 4.	0.421
MET	RNASEL	ENSLACP00000015263	ENSLACP00000000894	MET proto-oncogene, receptor tyrosine kinase.	Uncharacterized protein.	0.401