Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LNPEPLeucyl and cystinyl aminopeptidase. (1035 aa)    
Predicted Functional Partners:
TNKS2
Poly [ADP-ribose] polymerase.
   
 
 0.779
TNKS
Poly [ADP-ribose] polymerase.
   
 
 0.564
TBC1D1
TBC1 domain family member 1.
     
 0.560
LOC102366063
PID domain-containing protein.
     
 0.560
TBC1D4
TBC1 domain family member 4.
     
 0.560
AGT
SERPIN domain-containing protein; Belongs to the serpin family.
   
 0.550
RPA2
Replication protein A2.
   
 
 0.521
TBC1D31
TBC1 domain family member 31.
   
  
 0.520
TPP2
Tripeptidyl peptidase 2.
   
 
 0.507
DDX56
DEAD-box helicase 56.
   
 
 0.499
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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