Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H3A6S4_LATCHTPR_REGION domain-containing protein. (405 aa)    
Predicted Functional Partners:
RSAD2
Radical S-adenosyl methionine domain containing 2.
   
 0.818
IFIH1
Interferon induced with helicase C domain 1.
   
 0.740
LOC102354416
Uncharacterized protein.
   
 0.726
EIF2AK2
Protein kinase domain-containing protein.
   
 0.649
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
    
 0.631
ADAR
Adenosine deaminase RNA specific.
   
 
 0.590
CMPK2
Cytidine/uridine monophosphate kinase 2.
  
  
 0.582
ITFG2
Integrin alpha FG-GAP repeat containing 2.
     
  0.582
H3A339_LATCH
Uncharacterized protein.
   
 
 0.560
PHACTR4
Phosphatase and actin regulator.
    
   0.559
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.